We explored how coenzyme Q10 (CoQ10), a natural compound found in various foods, impacts blood clotting functions. Through a well-structured study, we utilized a randomized, double-blind, placebo-controlled trial with dyslipidemic patients, alongside in vitro tests on human platelets.
Our findings demonstrated that CoQ10 effectively reduces platelet aggregation, granule secretion, platelet spreading, and clot retraction. This means that CoQ10 can help prevent excessive blood clot formation, which is crucial for cardiovascular health.
We observed that CoQ10 works mainly by enhancing a signaling pathway involving cyclic AMP (cAMP) which ultimately diminishes the signaling of integrin αIIbβ3, a key player in platelet function. In addition, the treatment showed promising results in reducing thrombus growth in an animal model, suggesting significant in vivo benefits as well.
This study highlights the potential of CoQ10 supplementation as a protective measure for individuals at risk of cardiovascular diseases by regulating platelet-related processes involved in clotting.
Read More
9
CoQ10 reduces blood clot risk
Mitochondrial dysfunction in antiphospholipid syndrome: implications in the pathogenesis of the disease and effects of coenzyme Q(10) treatment.
We investigated how coenzyme Q(10) (CoQ(10)) affects blood clot risk in patients with antiphospholipid syndrome (APS), particularly focusing on oxidative stress and mitochondrial dysfunction. Our analysis compared 43 APS patients with 38 healthy individuals.
We observed a notable increase in prothrombotic and inflammatory indicators in the APS group. Specifically, the resurgence of oxidative stress was marked by higher peroxide production and altered mitochondrial function in their blood cells.
To explore the potential benefits of CoQ(10), we preincubated healthy monocytes with it before exposing them to dangerous IgG-antiphospholipid antibodies. Remarkably, CoQ(10) treatment reduced oxidative stress, improved mitochondrial health, and decreased the production of critical proteins associated with clotting and inflammation.
These findings suggest that CoQ(10) might help restore balance in the body's systems, reducing the risk of blood clots in individuals with APS by targeting the underlying oxidative mechanisms. Overall, our research points to the promise of CoQ(10) as a therapeutic option for APS patients facing increased blood clot risks.
Read More
8
Ubiquinol reduces clot risk markers
Ubiquinol Effects on Antiphospholipid Syndrome Prothrombotic Profile: A Randomized, Placebo-Controlled Trial.
We conducted a randomized, controlled trial to explore how ubiquinol, a form of coenzyme Q10, affects markers of inflammation and blood clotting in patients with antiphospholipid syndrome (APS), a condition linked to an increased risk of blood clots.
In this study, thirty-six APS patients were assigned to receive either ubiquinol or a placebo for one month. Of these, thirty-three completed the intervention. The results showed that ubiquinol significantly raised plasma levels of coenzyme Q, which in turn improved endothelial function, a crucial factor for maintaining proper blood flow and reducing clot risk.
Notably, we observed that ubiquinol decreased the expression of certain proteins tied to blood clotting and inflammation. It also inhibited specific biochemical pathways associated with thrombosis while improving mitochondrial health within cells. This suggests a potential dual benefit: reducing inflammation and enhancing cellular health may help manage the prothrombotic profile seen in APS.
Overall, our findings indicate that ubiquinol could serve as a beneficial adjunct therapy in APS treatment, with minimal side effects and promising therapeutic potential regarding blood clot risk.
Read More
Most Useful Reviews
9
Cholesterol nearly normal
1 people found this helpful
I purchased this for my husband, who has high cholesterol. After three months of use, his cholesterol levels dropped nearly to normal. I recommend it to anyone with high cholesterol.
Read More
7.5
Satisfactory results
1 people found this helpful
After taking Red Yeast Rice, I noticed a significant reduction in LDL cholesterol. This product supplements CoQ10, doubling the benefits at a reasonable price. A colleague also showed satisfactory progress after trying it.
Read More
9
Effective treatment
I take one capsule daily along with one omega-3 capsule. After two months, my cholesterol decreased by 25%. The capsules are easy to swallow and the 120-capsule package is enough for four months. I'm very pleased with this product.
We explored how coenzyme Q10 (CoQ10), a natural compound found in various foods, impacts blood clotting functions. Through a well-structured study, we utilized a randomized, double-blind, placebo-controlled trial with dyslipidemic patients, alongside in vitro tests on human platelets.
Our findings demonstrated that CoQ10 effectively reduces platelet aggregation, granule secretion, platelet spreading, and clot retraction. This means that CoQ10 can help prevent excessive blood clot formation, which is crucial for cardiovascular health.
We observed that CoQ10 works mainly by enhancing a signaling pathway involving cyclic AMP (cAMP) which ultimately diminishes the signaling of integrin αIIbβ3, a key player in platelet function. In addition, the treatment showed promising results in reducing thrombus growth in an animal model, suggesting significant in vivo benefits as well.
This study highlights the potential of CoQ10 supplementation as a protective measure for individuals at risk of cardiovascular diseases by regulating platelet-related processes involved in clotting.
Read More
9
CoQ10 reduces blood clot risk
Mitochondrial dysfunction in antiphospholipid syndrome: implications in the pathogenesis of the disease and effects of coenzyme Q(10) treatment.
We investigated how coenzyme Q(10) (CoQ(10)) affects blood clot risk in patients with antiphospholipid syndrome (APS), particularly focusing on oxidative stress and mitochondrial dysfunction. Our analysis compared 43 APS patients with 38 healthy individuals.
We observed a notable increase in prothrombotic and inflammatory indicators in the APS group. Specifically, the resurgence of oxidative stress was marked by higher peroxide production and altered mitochondrial function in their blood cells.
To explore the potential benefits of CoQ(10), we preincubated healthy monocytes with it before exposing them to dangerous IgG-antiphospholipid antibodies. Remarkably, CoQ(10) treatment reduced oxidative stress, improved mitochondrial health, and decreased the production of critical proteins associated with clotting and inflammation.
These findings suggest that CoQ(10) might help restore balance in the body's systems, reducing the risk of blood clots in individuals with APS by targeting the underlying oxidative mechanisms. Overall, our research points to the promise of CoQ(10) as a therapeutic option for APS patients facing increased blood clot risks.
Read More
8
Ubiquinol reduces clot risk markers
Ubiquinol Effects on Antiphospholipid Syndrome Prothrombotic Profile: A Randomized, Placebo-Controlled Trial.
We conducted a randomized, controlled trial to explore how ubiquinol, a form of coenzyme Q10, affects markers of inflammation and blood clotting in patients with antiphospholipid syndrome (APS), a condition linked to an increased risk of blood clots.
In this study, thirty-six APS patients were assigned to receive either ubiquinol or a placebo for one month. Of these, thirty-three completed the intervention. The results showed that ubiquinol significantly raised plasma levels of coenzyme Q, which in turn improved endothelial function, a crucial factor for maintaining proper blood flow and reducing clot risk.
Notably, we observed that ubiquinol decreased the expression of certain proteins tied to blood clotting and inflammation. It also inhibited specific biochemical pathways associated with thrombosis while improving mitochondrial health within cells. This suggests a potential dual benefit: reducing inflammation and enhancing cellular health may help manage the prothrombotic profile seen in APS.
Overall, our findings indicate that ubiquinol could serve as a beneficial adjunct therapy in APS treatment, with minimal side effects and promising therapeutic potential regarding blood clot risk.
Read More
8
CoQ10 improves plaque quality
Effect of coenzyme Q10 on experimental atherosclerosis and chemical composition and quality of atheroma in rabbits.
We conducted a study to see how coenzyme Q10 (CoQ10) treatment affects blood clotting, particularly in the context of atherosclerosis. In our controlled trial involving rabbits, we compared the effects of CoQ10 with a placebo over 24 weeks while the animals were fed a diet high in trans fatty acids.
We observed that CoQ10 administration led to significant reductions in markers of oxidative damage, such as thiobarbituric acid reactive substances and malondialdehyde. These changes suggested that CoQ10 helped lower oxidative stress without directly affecting lipid levels.
Importantly, we found that the size and quality of atheromas, or plaques, were better in the group receiving CoQ10. Atherosclerosis scores and the presence of complications like ulceration or thrombosis were also notably lower compared to the placebo group. However, while we noted improvements in plaque quality and associated factors, the effects specific to blood clotting were not directly examined in terms of statistical significance.
Overall, our findings suggest that while coenzyme Q10 might benefit atherosclerosis and enhance plaque quality, its effects specifically on blood clotting remain less clear. Further research could clarify this aspect.
Read More
8
CoQ10 effects on blood clotting
Could coenzyme Q10 affect hemostasis by inhibiting platelet vitronectin (CD51/CD61) receptor?
We explored the effects of coenzyme Q10 (CoQ10) on blood clotting mechanisms and specifically how it influences platelets. In our study, we had 15 human participants and 10 swine who received 100 mg of CoQ10 twice a day for 20 days, alongside their regular diet. This regimen led to a remarkable three-fold increase in total serum CoQ10 levels.
During this period, we observed noteworthy declines in several important markers associated with blood clotting, including plasma fibronectin, thromboxane B2, prostacyclin, and endothelin-1. One of the most significant findings was the consistent inhibition of the vitronectin receptor on platelets throughout the treatment. This suggests that CoQ10 might directly affect how platelets function, potentially reducing the risk of dangerous blood clots.
Overall, our research outlines how dietary CoQ10 could play a role in managing blood clotting by impacting platelet behavior. These results may help explain why CoQ10 supplementation has been associated with fewer thrombotic complications in certain patients.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 18 Reviews
7.9
All Reviews
Positive Reviews
Negative Reviews
9
Cholesterol nearly normal
1 people found this helpful
I purchased this for my husband, who has high cholesterol. After three months of use, his cholesterol levels dropped nearly to normal. I recommend it to anyone with high cholesterol.
Read More
7.5
Satisfactory results
1 people found this helpful
After taking Red Yeast Rice, I noticed a significant reduction in LDL cholesterol. This product supplements CoQ10, doubling the benefits at a reasonable price. A colleague also showed satisfactory progress after trying it.
Read More
9
Effective treatment
I take one capsule daily along with one omega-3 capsule. After two months, my cholesterol decreased by 25%. The capsules are easy to swallow and the 120-capsule package is enough for four months. I'm very pleased with this product.
Read More
7.5
Lowered cholesterol
8 people found this helpful
On my cardiologist's advice, I began taking RYR, as I couldn't take statins. My cholesterol fell from 308 to 283 over a month and a half, with HDL increasing from 41 to 43. Triglycerides dropped from 346 to 287, and LDL from 198 to 183. I look forward to seeing further improvements in three months, and there are no side effects like those from statins.
Read More
9
Improved cholesterol levels
6 people found this helpful
I bought this complex for my mother, who has elevated cholesterol. Red Yeast Rice is an excellent aid for maintaining clean arteries. It contains 100 mg of Coenzyme Q10 per dose, which is essential. We combined it with Omega and beta-sitosterol, achieving a remarkable decrease in bad cholesterol levels. Happy mum leads to happy children!
A blood clot is a mass of blood that changes from a liquid to a gel, effectively forming a plug that can stop bleeding. This natural process, known as coagulation, is critical for preventing excessive blood loss when you sustain an injury. Blood clots can occur in various areas of the body, typically at the site of a wound, but they can also form within blood vessels without an obvious injury, which may lead to serious health complications.
While blood clots are essential for healing, they can pose significant health risks if they form inappropriately. For example, a deep vein thrombosis (DVT) occurs when a clot forms in a deep vein, usually in the legs, and can travel to the lungs, causing a life-threatening condition called a pulmonary embolism. Risk factors for blood clots include prolonged immobility, certain medical conditions, and the use of specific medications, among others. It’s important to recognize the symptoms of abnormal clotting, such as swelling, pain, and redness in the affected area, and seek medical attention if they occur.
Red yeast rice is a traditional Chinese food and herbal supplement made by fermenting rice with a specific type of mold called Monascus purpureus. This fermentation process gives the rice its distinctive red color, as well as its potential health benefits. Historically, it has been used in Asian cuisine as a coloring agent and flavor enhancer, but it has gained popularity in the wellness community mainly for its cholesterol-lowering effects. The active compounds in red yeast rice include monacolins, particularly monacolin K, which is chemically similar to the active ingredient in statin medications used to manage cholesterol levels.
Numerous studies suggest that red yeast rice may effectively reduce total cholesterol and LDL (commonly referred to as "bad" cholesterol) levels. However, results can vary based on the dosage and specific product formulation, as the amount of active compounds in supplements can differ significantly. As with any supplement, it’s essential to consult with a healthcare professional before adding red yeast rice to your regimen, especially for individuals with existing health conditions or those taking medication, as it may interact with other treatments. Overall, while red yeast rice could offer benefits for heart health, it should be approached with consideration and care.
Based on user reviews, the time frame to see results from taking supplements for blood clot or cholesterol management can vary. Many users report noticing significant improvements within a month and a half to three months of consistent use. For instance, one user noted a reduction in cholesterol levels by 40% after a month and a half of taking the supplement (Read Review), while another mentioned returning to normal cholesterol levels after three months of daily intake (Read Review).
On the other hand, there were users who experienced less favorable results or no significant changes, even after extended use. A review highlighted that some individuals did not see a decrease in cholesterol despite several months of taking the supplement (Read Review). It’s essential to remember that individual responses can vary widely, and consulting a healthcare professional is advisable for tailored advice and the best management strategy for blood clot concerns.
Based on the current scientific research, coenzyme Q10 (CoQ10) shows promising potential in supporting blood clot management and reducing the risk of excessive clot formation. A study indicated that CoQ10 can diminish platelet aggregation and enhance signaling pathways that regulate clotting functions, which may significantly benefit patients at risk for cardiovascular complications [1]. Additionally, research on its reduced form, ubiquinol, revealed that it can lower inflammatory markers and specific proteins associated with clotting in patients with antiphospholipid syndrome, further hinting at its therapeutic potential [2].
Moreover, the effects of CoQ10 on blood clotting mechanisms have been documented in various settings, including studies demonstrating its ability to reduce oxidative stress in blood cells and improve overall mitochondrial health, which plays a crucial role in clotting processes [3]. While its direct effects on blood clotting need further exploration, the evidence suggests that CoQ10 supplementation may be beneficial for those concerned about blood clots, as it appears to positively influence platelet function and inflammatory responses associated with clot formation [5]. Overall, these findings advocate for considering CoQ10 as a supportive supplement in managing blood clot risks.
Users report a range of improvements in symptoms related to cholesterol management after taking Red Yeast Rice supplements. Many individuals have observed significant reductions in their cholesterol levels, with some users noting decreases of up to 40% in LDL cholesterol after approximately one and a half months of consistent use (Read Review). A user shared that their cholesterol levels dropped from 308 to 283 over six weeks, while another reported their levels fell to normal after three months of intake, which signifies the potential effectiveness of these supplements (Read Review; Read Review).
However, it is important to note that individual results can vary significantly. Some users have reported minimal changes in their cholesterol levels despite extended use, which highlights that not everyone experiences the same outcomes (Read Review; Read Review). Overall, while many users have had positive experiences with Red Yeast Rice, it is advisable to approach these supplements as part of a broader health strategy, including diet and regular check-ups with a healthcare provider.
Users report mixed experiences when combining Red Yeast Rice with other supplements for managing blood clot or cholesterol issues. Several individuals emphasized the benefits of pairing Red Yeast Rice with CoQ10, noting that this combination could enhance overall results. One user mentioned that while taking Red Yeast Rice, they also supplemented with CoQ10, claiming it doubled the benefits at a reasonable price (Read Review). Another user observed significant cholesterol reduction after combining Red Yeast Rice with omega-3 capsules and attributed a 25% decrease in cholesterol levels to this combination over two months (Read Review).
Conversely, not every user had positive outcomes. Some reported minimal or no effects on their cholesterol despite trying both Red Yeast Rice and other supplements. For instance, a user expressed disappointment as their parents experienced no improvement after several months, indicating that diet and lifestyle also play crucial roles (Read Review). It's evident from the experiences shared that while combining these supplements can yield positive results for some, individual responses vary and achieving the best outcomes may require a comprehensive approach.
Based on user reviews, there seems to be a range of reported dosages for Red Yeast Rice, with users experimenting to find what works best for them. Some individuals have found success with a lower dose, such as one capsule daily, reporting significant reductions in cholesterol levels after two months (Read Review). Others suggested higher dosages, like four tablets daily, which led to marked improvements in their cholesterol levels within a month (Read Review). A common theme is the inclusion of Coenzyme Q10 alongside Red Yeast Rice, which users noted enhanced the overall effectiveness of the supplement (Read Review).
Users emphasize that individual results can vary greatly, with some achieving near-normal cholesterol levels while others experienced minimal improvements even after several months (Read Review; Read Review). Regardless of the specific dosage, many agree that a balanced diet and exercise remain crucial to maximizing the benefits of Red Yeast Rice for heart health.
9
40% cholesterol drop
1 people found this helpful
After consistently taking it for a month and a half, my cholesterol dropped by 40% and returned to a normal range. For blood lipid issues, I highly recommend this supplement alongside diet and exercise.
9
Achieved normal cholesterol
6 people found this helpful
I had high cholesterol and began taking one pill every evening. After three months, my blood test results returned to normal. I am so pleased that I am continuing to take it.
2
No effect noted
3 people found this helpful
Unfortunately, this product did not help my elderly parents reduce their cholesterol levels despite several months of use. Their blood tests and personal experiences showed no improvement, leading us to try a different brand, which worked perfectly.
7.5
Lowered cholesterol
8 people found this helpful
On my cardiologist's advice, I began taking RYR, as I couldn't take statins. My cholesterol fell from 308 to 283 over a month and a half, with HDL increasing from 41 to 43. Triglycerides dropped from 346 to 287, and LDL from 198 to 183. I look forward to seeing further improvements in three months, and there are no side effects like those from statins.
4
No noticeable change
I didn’t notice any difference in my cholesterol despite taking red yeast rice regularly. My blood tests didn’t show significant changes, so I won't use it again, though I understand experiences may vary.
7.5
Satisfactory results
1 people found this helpful
After taking Red Yeast Rice, I noticed a significant reduction in LDL cholesterol. This product supplements CoQ10, doubling the benefits at a reasonable price. A colleague also showed satisfactory progress after trying it.
9
Effective treatment
I take one capsule daily along with one omega-3 capsule. After two months, my cholesterol decreased by 25%. The capsules are easy to swallow and the 120-capsule package is enough for four months. I'm very pleased with this product.
7.5
Cholesterol drop
1 people found this helpful
Blood tests showed cholesterol levels exceeded 190, so I took four tablets daily. After a month, my levels dropped to 130. No special side effects occurred, and I was satisfied with the outcome.
9
Improved cholesterol levels
6 people found this helpful
I bought this complex for my mother, who has elevated cholesterol. Red Yeast Rice is an excellent aid for maintaining clean arteries. It contains 100 mg of Coenzyme Q10 per dose, which is essential. We combined it with Omega and beta-sitosterol, achieving a remarkable decrease in bad cholesterol levels. Happy mum leads to happy children!
9
CoQ10 reduces harmful blood clots
Coenzyme Q10 Upregulates Platelet cAMP/PKA Pathway and Attenuates Integrin αIIbβ3 Signaling and Thrombus Growth.
We explored how coenzyme Q10 (CoQ10), a natural compound found in various foods, impacts blood clotting functions. Through a well-structured study, we utilized a randomized, double-blind, placebo-controlled trial with dyslipidemic patients, alongside in vitro tests on human platelets.
Our findings demonstrated that CoQ10 effectively reduces platelet aggregation, granule secretion, platelet spreading, and clot retraction. This means that CoQ10 can help prevent excessive blood clot formation, which is crucial for cardiovascular health.
We observed that CoQ10 works mainly by enhancing a signaling pathway involving cyclic AMP (cAMP) which ultimately diminishes the signaling of integrin αIIbβ3, a key player in platelet function. In addition, the treatment showed promising results in reducing thrombus growth in an animal model, suggesting significant in vivo benefits as well.
This study highlights the potential of CoQ10 supplementation as a protective measure for individuals at risk of cardiovascular diseases by regulating platelet-related processes involved in clotting.
8
Ubiquinol reduces clot risk markers
Ubiquinol Effects on Antiphospholipid Syndrome Prothrombotic Profile: A Randomized, Placebo-Controlled Trial.
We conducted a randomized, controlled trial to explore how ubiquinol, a form of coenzyme Q10, affects markers of inflammation and blood clotting in patients with antiphospholipid syndrome (APS), a condition linked to an increased risk of blood clots.
In this study, thirty-six APS patients were assigned to receive either ubiquinol or a placebo for one month. Of these, thirty-three completed the intervention. The results showed that ubiquinol significantly raised plasma levels of coenzyme Q, which in turn improved endothelial function, a crucial factor for maintaining proper blood flow and reducing clot risk.
Notably, we observed that ubiquinol decreased the expression of certain proteins tied to blood clotting and inflammation. It also inhibited specific biochemical pathways associated with thrombosis while improving mitochondrial health within cells. This suggests a potential dual benefit: reducing inflammation and enhancing cellular health may help manage the prothrombotic profile seen in APS.
Overall, our findings indicate that ubiquinol could serve as a beneficial adjunct therapy in APS treatment, with minimal side effects and promising therapeutic potential regarding blood clot risk.
9
CoQ10 reduces blood clot risk
Mitochondrial dysfunction in antiphospholipid syndrome: implications in the pathogenesis of the disease and effects of coenzyme Q(10) treatment.
We investigated how coenzyme Q(10) (CoQ(10)) affects blood clot risk in patients with antiphospholipid syndrome (APS), particularly focusing on oxidative stress and mitochondrial dysfunction. Our analysis compared 43 APS patients with 38 healthy individuals.
We observed a notable increase in prothrombotic and inflammatory indicators in the APS group. Specifically, the resurgence of oxidative stress was marked by higher peroxide production and altered mitochondrial function in their blood cells.
To explore the potential benefits of CoQ(10), we preincubated healthy monocytes with it before exposing them to dangerous IgG-antiphospholipid antibodies. Remarkably, CoQ(10) treatment reduced oxidative stress, improved mitochondrial health, and decreased the production of critical proteins associated with clotting and inflammation.
These findings suggest that CoQ(10) might help restore balance in the body's systems, reducing the risk of blood clots in individuals with APS by targeting the underlying oxidative mechanisms. Overall, our research points to the promise of CoQ(10) as a therapeutic option for APS patients facing increased blood clot risks.
8
CoQ10 effects on blood clotting
Could coenzyme Q10 affect hemostasis by inhibiting platelet vitronectin (CD51/CD61) receptor?
We explored the effects of coenzyme Q10 (CoQ10) on blood clotting mechanisms and specifically how it influences platelets. In our study, we had 15 human participants and 10 swine who received 100 mg of CoQ10 twice a day for 20 days, alongside their regular diet. This regimen led to a remarkable three-fold increase in total serum CoQ10 levels.
During this period, we observed noteworthy declines in several important markers associated with blood clotting, including plasma fibronectin, thromboxane B2, prostacyclin, and endothelin-1. One of the most significant findings was the consistent inhibition of the vitronectin receptor on platelets throughout the treatment. This suggests that CoQ10 might directly affect how platelets function, potentially reducing the risk of dangerous blood clots.
Overall, our research outlines how dietary CoQ10 could play a role in managing blood clotting by impacting platelet behavior. These results may help explain why CoQ10 supplementation has been associated with fewer thrombotic complications in certain patients.
References
Ya F, Xu XR, Shi Y, Gallant RC, Song F, et al. Coenzyme Q10 Upregulates Platelet cAMP/PKA Pathway and Attenuates Integrin αIIbβ3 Signaling and Thrombus Growth. Mol Nutr Food Res. 2019;63:e1900662. 10.1002/mnfr.201900662
Pérez-Sánchez C, Aguirre MÁ, Ruiz-Limón P, Ábalos-Aguilera MC, Jiménez-Gómez Y, et al. Ubiquinol Effects on Antiphospholipid Syndrome Prothrombotic Profile: A Randomized, Placebo-Controlled Trial. Arterioscler Thromb Vasc Biol. 2017;37:1923. 10.1161/ATVBAHA.117.309225
Perez-Sanchez C, Ruiz-Limon P, Aguirre MA, Bertolaccini ML, Khamashta MA, et al. Mitochondrial dysfunction in antiphospholipid syndrome: implications in the pathogenesis of the disease and effects of coenzyme Q(10) treatment. Blood. 2012;119:5859. 10.1182/blood-2011-12-400986
Singh RB, Shinde SN, Chopra RK, Niaz MA, Thakur AS, et al. Effect of coenzyme Q10 on experimental atherosclerosis and chemical composition and quality of atheroma in rabbits. Atherosclerosis. 2000;148:275.
Serebruany VL, Gurbel PA, Ordoñez JV, Herzog WR, Rohde M, et al. Could coenzyme Q10 affect hemostasis by inhibiting platelet vitronectin (CD51/CD61) receptor?. Mol Aspects Med. 1997;18 Suppl:S189.